MRV CCSVI Testing for Chronic Venous Disease

Testing is provided by the Applied fMRI Institute in San Diego, CA, using a Siemens 3T MRI, and conducted under IRB approval.

If you have any questions regarding which test you should have, please Contact Hubbard Foundation.

CCSVI Test shows Jugular Vein Obstructions

Above: CCSVI Test shows Jugular
Vein Obstructions

Hubbard CCSVI Testing Protocol*

MRV and Flow- to measure flow and anatomy of the jugular veins (the veins that drain blood from the brain)
Research MRI protocols added (no cost):
         Perfusion-  to measure fluid flow within the brain tissue

*We request that you return  the day after your treatment for a follow-up test for comparison pre and post (no cost) 

Test Fee: $1,200 (payable to Applied fMRI Institute)
Insurance Code:     70546, MRV of head without contrast

Or, Haacke CCSVI Testing Protocol
MRV and Flow- to measure flow and anatomy of the jugular and azygos veins (the veins that drain blood from the brain and spinal cord)
MRI of the head with and without contrast- to evaluate new and old plaques, using Gadolinium enhancing contrast
SWI- to measure iron deposition

Test Fee: $3,500 (payable to Applied fMRI Institute)
Insurance Codes:  70553  MRI with and without contrast
                              70546  MRV head with and without contrast
                              70549  MRV neck with and without contrast


CLICK HERE for Scheduling


Proper CCSVI Testing

We’ve been reluctant to discuss this issue, for fear it would appear self-serving since we run an MRI research facility (Devin Hubbard runs the Applied fMRI Institute) . But let's talk about proper CCSVI testing, MR-Venography and Doppler Ultrasound.

Doppler is inexpensive. Every IR (interventional radiologist) including ours have them in their offices. They can visualize the appearance of the veins and transient direction of flow.

MR does so much more:

  1. It shows the presence of MS lesions
  2. MR shows the appearance of veins better than Doppler can
  3. It not only shows the direction of flow but calculates objectively (independent of Doppler operator expertise) an exact speed of flow in ml/sec.
  4.  MR can show whether iron is accumulating abnormally
  5. It can show drainage from the cortex of the brain itself directly using fMRI BOLD (the Hubbard method).

Your IR doesn’t need the Doppler to do his procedure. But you need MR to track the course of your illness. This information is the baseline from which you will judge what happens in the future.


Still Unknown (needs more research)

Which is more important, reflux or flow volume (ml/sec). We have collected data on this question in over 200 subjects (to date 3/7/2011) and will soon be able to answer the question:

  1. Which better predicts re-stenosis and or clinical improvement, presence of reflux or the flow rate.
  2. Which method, Doppler or MR flow is more sensitive at identifying reflux?

Since the studies to date have used MR only to look at vein appearance, not to calculate flow, the answer to this question is still unknown. We would do this study ourselves but it remains unclear whose Doppler method is best. Many have claimed to be the best but since it’s subjective, how do we know objectively which method is best?

Dr. Hubbard will be publishing in March, our finding that the cerebral cortex of the brain BOLD venous is abnormal in MS and normalizes after venoplasty. But ultimately the clinical outcome improvement in symptoms is what must determine the need for repeat venoplasty CCSVI treatment.


Testing Location:

The Applied fMRI Institute
10065 Old Grove Rd.
Suite 103 (enter through the back of the building)
San Diego, CA 92131